Here are the best Cocaine mixes in Schedule I! Whether you want to see high sell prices, or opt for the most efficient mix, we have them.
So you're nearing the endgame of Schedule I, and you want to maximize profits. Here are the best Cocaine mixes you can do in Schedule I, from the mix with the highest selling price to the one with the highest profit margin.
Schedule I - Most expensive Cocaine mix
The most expensive cocaine mix found so far in Schedule I requires eight ingredients and has eight effects.
You need to mix the ingredients in the following order:
- Motor Oil
- Cuke
- Paracetamol
- Gasoline
- Cuke
- Battery
- Horse Semen
- Mega Bean
This product's effects are: Anti-Gravity, Glowing, Tropic Thunder, Zombifying, Cyclopean, Bright-Eyed, Long Faced, Foggy.
The ingredients themselves cost $42.00, and the base sell price for the resulting mix is $735. This is a 1,750% profit margin, but doesn't account for the other items in the process, like the plants, soil, additives, or workers. Of course, you can still upsell the product to have a higher sell price and increase profits.

This isn't the most efficient mix, but if you want to sell big numbers, this is the one to go for.
Automation
To automate this mix, you'll need two Chemists to work the mixing stations and at least one Handler to replenish the ingredients. The minimum workers you need to completely automate the process from the beginning is:
- three Chemists
- two Handlers
- one Botanist
The additional Chemist and Handler will work on the Cauldron and Lab Oven, while the Botanist will take care of the plants.
One of the Handlers can operate the Brick Press, but you'll need one more if you want it packaged in jars or bags.
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Most efficient Cocaine mix in Schedule I
Here is the most efficient cocaine mix found in Schedule I, involving four ingredients. This is the sweet spot since one chemist can operate up to four Mixing Stations.
For this mix, you need the following ingredients in order:
- Banana
- Cuke
- Horse Semen
- Mega Bean
You'll end up with a product with the effects Electrifying, Cyclopean, Long Faced, Foggy.
The ingredients will set you back $20, but the product will sell for at least $441 for a 2,205% profit margin, once again not counting the other expenses.
Automation

Since the mix falls at an even four, you need only one Chemist for the mixing part of the automation process. This brings the minimum roster of workers to:
- one Botanist
- two Chemists
- one Handler
One Handler is enough to replenish the Cauldron and the Mixing Stations.
Schedule I continues to be a popular game on Steam and is receiving constant updates from its solo developer, TVGS.